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The purpose of this study is to study the evolution of early life risk factors that may lead to cancer and other conditions. This is a prospective cohort study of families who reside in Minnesota.

Throat cancer linked to HPV is on the rise. While most people clear the HPV virus naturally, it can sometimes stay and cause throat cancer. Our research studies how mouth bacteria may help or hurt this process. We hope to develop simple, low-cost tests for early detection at the dentist. Participation involves a survey, spitting into a tube and getting a quick swab of your tonsils to collect microbes. This study is available at the D2D Building at the Minnesota State Fair.

Microbes in the oral cavity can cause diseases such as cavities and infected root canals. One genus of bacteria, Enterococcus, is also commonly found in the gastrointestinal tract and as an opportunistic pathogen in healthcare-associated infections. Currently, there are very few isolates of Enterococcus species that have been obtained from the oral cavity. Enterococcus species can interact with other oral microbes, including bacteria, fungi, and bacteriophage, and this may contribute to the development of oral infections. We seek to collect oral isolates of Enterococcus, Streptococcus, bacteriophages, and fungi like Candida albicans to further our research on biofilm development and virulence of these bacteria. In this study, oral rinse samples will be collected from adults at the MN State Fair for isolation of microbes and sequencing of microbial DNA. This study is only available at the D2D Building at the Minnesota State Fair.

The goal of this observational study is to learn more about associations between respiratory infections, changes in the microbiome of the nose and upper throat, and juvenile idiopathic arthritis (JIA).

This is a study that will investigate the relationship between visual attention and memory and brain dynamics in healthy volunteers by manipulating brain oscillations with transcranial alternating current stimulation (tACS).

This study aims to take an explorative approach to (1) characterize mind-body experiences of both caregivers and non-caregivers, (2) identify potential differences between caregivers and non-caregivers, and (3) describe mind-body experiences among caregivers across the care continuum (e.g. caring for elderly, caring for children with disabilities, caring for children without disabilities). This study is only available at the D2D Building at the Minnesota State Fair.

This study is about the patterns and characteristics of how individuals drink alcohol, especially at events like the state fair. This study is only available at the Minnesota State Fair in the D2D Building.

This study is available at the Minnesota State Fair. According to the Minnesota Department of Human Services, about 290,000 adults in Minnesota need treatment for addiction. National data suggests that only 10% of those who need treatment receive it. The goal of the study is to determine public opinion and knowledge about opioid use disorder and its treatment.

This study will ask families to complete a survey to help us learn more about how families with children between the ages of 2-6 years old experience mealtime and feeding challenges at home. We aim to understand more about the needs of families with young children around mealtime challenges to provide better supports, knowledge, and services in the future. You may participate in this study at the State Fair on Sunday, August 24 from 9:00 am to 2:00 pm or on Friday, August 29 from 2:30 pm to 9:00 pm.

This D2D study aims to examine the relationship between people’s responses to questionnaires about tinnitus and noise exposure and their ability to hear high-pitched sounds. To participate in this study, visit the D2D Building Minnesota State Fair on Tuesday, 8/26 from 9 am - 2 pm and Friday, 8/29 from 2:30 pm - 9 pm

In this study, we want to find out more about secondhand smoke from shisha smoking in the home. We want to help families learn more about the risks of shisha smoke in the home and find ways to stop smoking at home.

We will enroll healthy pregnant women (following enrollment, all subsequent study procedures will be completed postpartum) or postpartum women on hormonal birth control or no hormonal birth control with either a recent history of smoking and a desire to remain abstinent after childbirth, or who are currently smoking and motivated to quit smoking. Participants will be recruited throughout the continental United States (US). Participants living in Minnesota (our clinical site) will receive a 12-week course of exogenous progesterone. Participants will be followed for six months with remote visits, self-administered surveys, and self-collection of dried blood spots to measure hormones and smoking-related biomarkers.

This study is being done to learn more about the influence of the menopausal transition on autonomic and vascular function in midlife females. Participants will have their vitals taken and height, weight and waist-to-hip ratio measurements done, complete questionnaires, have blood draws, have electrical activity of a nerve in the leg measured (optional), have blood vessel function measured in the arm, perform breathing exercises, and complete a cold pressor test (putting a hand in ice-cold water). Participants will also have a scan to measure body composition and bone density.

The purpose of this project is to provide new knowledge of the relationship between structural and functional changes in cortico-basal ganglia pathways and the severity of motor and non-motor deficits in humans with PD.

This is a study of persons who do and do not stutter between ages 4 and 65 years. This study is trying to figure out how attention skills influence memory, language, and speech fluency skills.

We will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cognitive task or a perceptual task while we are measuring the change in brain function with EEG. Please fill out the linked screening questionnaire to determine if you are eligible.

The purpose of this study is to characterize balance and postural control in children with autism spectrum disorder and those with typical development. Participants will be asked to complete one lab visit. During this visit, parents will be asked to complete questionnaires about their family demographics and child behaviors, and their child's balance performance will be assessed using a virtual reality-based balance assessment. We are recruiting two groups of parents and children with ages ranging between 5-15 years to participate in this study. One group will include children with a diagnosis of autism spectrum disorders and their parents and the other group will be typically developing children who have no developmental, neurological or medical conditions and their parents.

This research is being done to collect blood and placenta samples to better understand how pregnancy impacts the health of mother and child. The goal of this research is to better understand what causes some pregnancy complications and how this impacts the longer term health of mothers and children.

Respiratory illnesses, including ear and sinus infections, colds, and pneumonias, are among the most common infectious diseases affecting Minnesotans across their lifespan. These diseases can be caused by many different types of microbes—bacteria, viruses and fungi—and different types of microbes may require different kinds of treatment. This research is being done to learn more about the specific types of microbes that cause respiratory infections in children and adults across the state of Minnesota over time. Antimicrobial resistance happens when microbes develop the ability to defeat the drugs designed to kill them. Through this study, we will learn which types of genes are carried by microbes living in the respiratory tract by collecting and analyzing nasal and oral specimen.

The purpose of this study to examine the effects of cigarette smoking and drinking alcohol on the formation of DNA damage in the mouth. The overall goal is to identify DNA damage that may be important to the development of head and neck cancers.

This research study is for creating a registry of all ages with conditions in endocrine and both health. Registries are used very often these days by doctors and scientists to collect information and use to perform research into rare conditions. This registry will be part of a global registry, called "GloBE-Reg" with the University of Glasgow (Scotland) and with the University of MInnesota.

This study is to investigate, validate and address remaining technical challenges of new imaging techniques used on a portable MRI machine. The research study consists of a one-time study visit that could last approximately 2.5 hours.

This study will help to identify challenges and barriers to self-performing anal cancer screening tests, and may identify unique ways to make this form of screening easier, more cost-effective, and more frequently performed. We believe that it has the potential to minimize the frequency of both disease and death from anal cancer among high-risk patient groups.

Medications used to treat Parkinson's disease will be delivered using a sachet ; placed in the oral/buccal cavity (between cheek and gum of lower jaw). This study may be a good fit for you if you are healthy, between the ages of 18 and 65, and aren’t currently taking regular medications. We expect that you will be in this research study for one visit, approximately 7 hours total. Compensation and transportation expenses will be provided.

You are invited to take part in a survey to help us learn more about what people know and think about diseases that are spread by ticks and mosquitoes. This study is being conducted by the researchers at the University of Minnesota Medical School on the Duluth Campus. The goal is to understand how people feel about these diseases and how much they know about how to protect themselves.

This research is being done to better understand why people develop a type of heart failure where the heart contracts normally but does not relax well. By comparing levels of chemicals in the blood that are secreted by the body in subjects with normal hearts and in subjects with abnormal relaxation, we hope to gain a better understanding of why heart failure occurs.

This study involves testing auditory and speech perception using behavioral and non-invasive physiological measures in humans.

This study includes healthy adults between the ages of 21-70 who either use or do not cannabidiol (CBD) regularly. The purpose of this study is to learn about how CBD users and nonusers respond to stress. Participants must be willing to attend one in-person visit at the University of Minnesota Duluth campus

The rate of lung cancer screening is not optimal among Chinese American high-risk smokers, although there is a high lung cancer rate among this population. We want to validate the adapted Chinese Lung Cancer Screening Health Belief Scale, enable its usage in Chinese Americans, and further explore the relationship between lung cancer screening health beliefs and health behavior among Chinese Americans. We will also aim to identify the differences in health beliefs regarding lung cancer screening between high-risk populations in China and Chinese Americans, and to examine factors influencing these differences.