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Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

Recruiting

The purpose of this study is to test a new treatment for Alcohol Use Disorder that supports long-term abstinence. This new treatment uses transcranial direct current stimulation (tDCS) combined with cognitive training to decrease the chance of relapse. Additionally, we are interested in examining whether specific genetic differences are related to treatment outcomes. For this, we would collect a saliva sample from you. Providing a genetic sample (saliva) is optional and takes about 5 minutes.

I'm interested

All
18 Years to 65 Years old
This study is NOT accepting healthy volunteers
Inclusion Criteria:

• Meet the Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria for AUD
• Abstinent from alcohol use
• Must have the intention to remain in the Lodging Plus program until the end of the intervention portion of the study.
Exclusion Criteria:

• Any medical condition or treatment with neurological sequelae (i.e. stroke, tumor, loss of consciousness>30 min, HIV)
• A head injury resulting in a skull fracture or a loss of consciousness exceeding 30 minutes (i.e., moderate or severe TBI)
• Any contraindications for tDCS or MRI scanning (tDCS contraindication: history of seizures; MRI contraindications; metal implants, pacemakers or any other implanted electrical device, injury with metal, braces, dental implants, non-removable body piercings, pregnancy, breathing or moving disorder)
• Any primary psychotic disorder (e.g. schizophrenia, schizoaffective disorder); Participants with other treated and stable psychiatric disorders will be included
• Presence of a condition that would render study measures difficult or impossible to administer or interpret
• Primary current substance use disorder diagnosis on a substance other than alcohol except for caffeine or nicotine
• Clinical evidence for Wernicke-Korsakoff syndrome
• Left-handedness
• Entrance to the treatment program under a court mandate

Device: TaskFlow Transcranial Electrical Stimulation device, Behavioral: Executive Function Focused Cognitive Training

Alcohol Use Disorder, Addiction

Jazmin Camchong, PhD - camch002@umn.edu
Hannah Verdoorn - verdo018@umn.edu
N/A
NCT05062369
See this study on ClinicalTrials.gov

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