Characterization of Comorbid Post-traumatic Stress Disorder and Major Depressive Disorder Utilizing Ketamine as an Experimental Medicine Probe


Note: The Minneapolis Veterans Affairs (VA) Health Care Systems (MVAHCS) Institutional Review Board (IRB) will oversee this research study under the main protocol (#VAM-18-00364). This local protocol addendum addresses neuroimaging at the University of Minnesota Center for Magnetic Resonance Research (UMN CMRR). Please note that we have selected "No" to the Drugs question in ETHOS, as the VA IRB approval covers the Ketamine use; only neuroimaging at CMRR is included in the UMN IRB portion of this study.

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Major Depressive Disorder, Post-Traumatic Stress Disorders

adjuvants, anesthesia, analgesics, anesthetics, anesthetics, dissociative, anesthetics, general, anesthetics, intravenous, anxiety disorders, behavioral symptoms, central nervous system agents, central nervous system depressants, depression, depressive disorder, depressive disorder, treatment-resistant, excitatory amino acid agents, excitatory amino acid antagonists, hypnotics and sedatives, ketamine, mental disorders, molecular mechanisms of pharmacological action, mood disorders, neurotransmitter agents, peripheral nervous system agents, pharmacologic actions, physiological effects of drugs, psychotropic drugs, sensory system agents, stress disorders, post-traumatic, stress disorders, traumatic, therapeutic uses

Sey Lee -
Cristina Albott
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