StudyFinder
Autonomic regulation of blood pressure in premature and early menopausal women
Recruiting
The goal of this study is to learn more about the effects of menopause on women's blood pressure and heart health. We are looking for women between the ages of 35 and 70 years to participate in the study. Participants may be pre- or postmenopausal; we are specifically interested in evaluating the influence of premature (< age 40 years) and early (< age 46 years) menopause.
Female
18 years and over
Inclusion Criteria:
• 35 to 70 years old
• experienced premature (less than 40 years old) or early (45 or younger) menopause OR
• premenopausal 35-49 years of age OR
• typical-age menopause who are between 50-70 years old
• menopause will be confirmed by report of amenorrhea for 12 months
Exclusion Criteria:
• nicotine or tobacco use within the past six months
• have diabetes or asthma
• diagnosed significant carotid stenosis
• additional medical diagnosis (study staff will review)
• women who are pregnant or breastfeeding
Diagnostic Test: Baroreflex sensitivity testing, Diagnostic Test: Blood tests, Diagnostic Test: Microneurography to measure muscle sympathetic nerve activity (MSNA), Diagnostic Test: Sympathoexcitatory Maneuvers
Heart & Vascular, Women's Health
Blood Pressure, Early Menopause, Hypertension, Menopause