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Measurement of Glucose Homeostasis in Human Brain by NMR: Effect of Recurrent Hypoglycemia on Type 1 Diabetes (Aim 2)

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Individuals with type 1 diabetes often develop an impaired awareness of hypoglycemia (IAH), meaning they are not fully aware of having low blood glucose levels. This research study is looking to determine what happens in the brain after repeat episodes of hypoglycemia.

I'm interested

Male or Female
18 years and over
Inclusion Criteria:

• 18 to 65 years old
• diagnosis of Type 1 diabetes
• diabetes duration 2 - 30 years
• Hemoglobin A1C less than 8.5%
Exclusion Criteria:

• unaware of hypoglycemia when it is occurring
• pregnant or plan to become pregnant during the study
• uncontrolled hypertension (blood pressure greater than 145/95 mmHg)
• inability to undergo MRI scanning, including but not limited to unable to remain still in an MRI scanner for more than 30 minutes, claustrophobia, presence of paramagnetic substances or pacemakers in body, weight over 300 pounds
• other medical or mental health issues (study staff will review)

Diabetes & Endocrine

Diabetes Mellitus, Type 1

Diabetes Study - studydiabetes@umn.edu
Elizabeth Seaquist
NA
STUDY00008108
See this study on ClinicalTrials.gov

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