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Algorithms for programming DBS systems for ET

Recruiting
This study seeks to leverage subject-specific computational models that can predict neural activation of axonal pathways adjacent to the active electrode(s) and implicated in the therapeutic mechanisms of Vim-DBS to in turn guide clinicians with which stimulation settings are likely to be the most therapeutic on tremorous activity.
All
21 Years to old
Inclusion Criteria:
diagnosis of ET
medication-refractory tremor
VIM-DBS implant (unilateral or bilateral)
7T MRI pre-operative scan under Dr. Harel's IRB (institutional review board) protocol (#1210M22183)
Post-operative CT scan
Exclusion Criteria:
history of musculoskeletal disorders that affect movement of the limbs
other significant neurological disorder
prior history of stereotactic neurosurgery (other than VIM-DBS surgery)
pregnancyDevice: Vim-Deep Brain Stimulation
Essential Tremor
Clinics and Surgery Center (CSC)
Marina Bryants - bryan371@umn.edu
Matthew Johnson
N/A
STUDY00005218
STUDY00005218
See this study on ClinicalTrials.gov