Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)


COPDGene is now in Phase 3: COPDGene has been funded for an additional five years by the US National Heart, Lung, and Blood Institute as well as the COPD Foundation. In addition to the cross-sectional subject data collected in the baseline and five year follow up COPDGene study visits, disease progression and incidence of COPD in smokers are important additional endpoints for genetic association studies. 10,371 subjects enrolled in Phase 1 study-wide. The U of MN enrolled 63 subjects in Phase 1. For Phase 3, we will invite original subjects who are still alive to return for a third evaluation ten years after their initial visit to assess disease incidence and/or progression in COPDGene subjects.

I'm interested

45 Years to 80 Years old
This study is also accepting healthy volunteers
Inclusion Criteria:

• At least 10 pack-years of cigarette smoking (although a of nonsmoking controls is also being enrolled)
• Self-designation of non-Hispanic white or African-American
Exclusion Criteria:

• Other lung diseases (except for asthma in participants with COPD)
• Pregnant
• Cancer (other than skin cancer) in the 5 years prior to study entry
• Received antibiotics for a COPD exacerbation in the 1 month prior to study entry
• First- or second-degree relative of a previously enrolled study participant

Pulmonary Disease, Chronic Obstructive, Emphysema, Bronchitis, Chronic

Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Chronic Bronchitis, Genetics, Association Studies, Computed Tomography

Mary Bailey -
Joanne Billings
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