StudyFinder

Search Results Within Category "Ear, Nose & Throat"

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

Search all categories
9 Study Matches

Identifying hearing loss through neural responses to engaging stories

This research study will develop an efficient electroencephalographic (EEG) method that uses narrated stories to identify frequency-specific hearing loss.

Melissa Polonenko
18 years and over
This study is also accepting healthy volunteers
STUDY00017008
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• Group 1: Adults aged 18-70 years, normal hearing, no history of neurological problems or ANSD
• Group 2: Adults aged 18-70 years, hearing loss with thresholds better than 70 dB HL, no history of neurological problems or ANSD, doesn?t wear a cochlear implant
Exclusion Criteria:

• Neurological problems
• ANSD
• Wears a cochlear implant
Ear, Nose & Throat
Hearing, Hearing loss, Listening, electrophysiology, and stories, books
I'm interested
Share via email

The Parallel Auditory Brainstem Response

This study aims to test the accuracy and speed of the pABR for future clinical use by recruiting adults with a range of hearing loss profiles from normal hearing to severe loss.

Melissa Polonenko
18 years and over
This study is NOT accepting healthy volunteers
SITE00001873
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• age 18-65 years
• hearing loss (can be from none to severe)
• no history of auditory neuropathy spectrum disorder or cochlear implant use
• can remain still or sleep for the test duration
Exclusion Criteria:

• profound hearing loss (thresholds > 80 dB HL)
• cochlear implant use
• auditory neuropathy spectrum disorder
• abnormal tympanogram
• inability to sleep or remain very still for the duration of the test
Ear, Nose & Throat
electrophysiology, Hearing, Hearing loss, Listening
I'm interested
Share via email

Listening effort in people with hearing impairment

The purpose of this research is to understand the effort needed to understand speech if hearing is impaired. Listening effort is higher in people with hearing impairment and has wide-ranging negative consequences across many aspects of a person’s life. The goal of this project is to explore factors that make listening effortful, with special focus on the need to repair perceptual mistakes by relying on context.

Matthew Winn
18 years and over
This study is also accepting healthy volunteers
STUDY00004150
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• There are two categories of participants: either people with cochlear implant (one or two cochlear implants) or people with normal hearing in both ears
Exclusion Criteria:

• non native English speakers
Ear, Nose & Throat
cochlear implant, hearing loss, listening
I'm interested
Share via email

The efficacy of incobotulinum toxin A injections for treatment of tinnitus: a randomized controlled trial

We are interested in the effects of injecting incobotulinum into muscles near the ear and neck to potentially reduce the symptoms of tinnitus. If successful, this procedure might reduce the burden many face by tinnitus. There are two stages of this study. The first stage, you may receive the study drug (incobtulinum) or a placebo. All participants will receive the study drug (incobtulinum) in the second stage.

Stephanie Standal
18 years and over
This study is NOT accepting healthy volunteers
STUDY00011665
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• unilateral or bilateral tinnitus present for at least 2 months
• score greater than 16 on the Tinnitus Handicap Inventory
Exclusion Criteria:

• known hypersensitivity to any botulinum toxin product
• received botulinum toxin for any medical reason in the past 4 months
• infection at proposed injection sites
• scheduled for neurological or otological surgery
• significant psychiatric history or associated diagnosis of major depression
• pregnant or breast feeding
Ear, Nose & Throat
Tinnitus
Visit study website
I'm interested
Share via email

Cochlear Implantation in Children with Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial

Kristin Gravel
Up to 18 years old
This study is also accepting healthy volunteers
STUDY00010956
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• Parents and child fluent in English
• Parents desire functional hearing in both ears for their child
• Severe to profound sensorineural hearing loss in one ear and normal hearing in the other ear
• If older than 5 years, documentation of progressive hearing loss (i.e. passed newborn hearing screening, or significant change in hearing)
Exclusion Criteria:

• Medical condition that contraindicates a cochlear implant, including abnormal hearing nerve
• Already using a cochlear implant
• Inability to complete study procedures
• Unrealistic expectations related to the benefits and limitations of cochlear implantation
• Unwillingness or inability to comply with all investigational requirement
Ear, Nose & Throat
Pediatric audiology, Audiology, Cochlear Implant, Single-Sided Deafness
I'm interested
Share via email
See this study on ClinicalTrials.gov

Assessments of sound perception and brain activation in response to paired sound and electrical stimulation of surface ear regions

We are investigating sound perception and brain activation effects in response to paired non-invasive electrical stimulation of surface body regions and sound stimulation. We aim to better understand the optimal conditions of paired electrical stimulation and sound, which opens opportunities for applying this method to improving hearing loss or helping with hearing disorders such as hearing loss, tinnitus, and hyperacusis. We are studying three groups of people: those with normal hearing, those with mild to moderate hearing loss, and those with tinnitus.

Hubert Lim
18 years and over
This study is also accepting healthy volunteers
STUDY00016992
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• normal hearing or hearing loss with or without tinnitus
• not users of Cochlear Implant or hearing aids
Ear, Nose & Throat
hearing loss, tinnitus, auditory plasticity, neuromodulation, transcutaneous electrical stimulation
I'm interested
Share via email

Measurement of Upper Aerodigestive Tract Pressures During Phonation

The purpose of this pilot research study is to test whether a tool called “High-Resolution Manometry” can diagnose laryngeal dystonia (also known as spasmodic dysphonia) and measure how well treatment works. High-Resolution Manometry measures pressures from a small catheter that is passed from your nose into your throat. We believe that pressures in the throat might be different for people with laryngeal dystonia than for people without laryngeal dystonia, or with other types of voice disorders. If we can diagnose laryngeal dystonia shortly after symptoms start, we can get patients the treatment they need sooner.

Jesse Hoffmeister
18 years and over
This study is also accepting healthy volunteers
STUDY00015206
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Patients with adductor laryngeal dystonia and:
• experienced improvement in voice quality following injection of botulinum toxin into the thyroarytenoid complex
• received their most-recent injection within 6 months
• age 18-80 years old
• able to read and write in English
• For Healthy Controls:
• age 18-80
• have no known voice problem
• able to read and write in English Patients with Muscle Tension Dysphonia:
• Age 18-80 (age-and sex matched to adductor laryngeal dystonia)
• Diagnosis of primary muscle tension dysphonia by a laryngologist and speech pathologist in the ?...absence of current organic vocal fold pathology, [and] without obvious?neurologic etiology.?18
• Able to read and write in English
• Muscle tension dysphonia patients who either haven?t started voice therapy, or for whom symptoms persisted despite voice therapy
Exclusion Criteria:
For people with adductor laryngeal dystonia, Muscle Tension Dysphonia and healthy controls:
• diagnosis of vocal tremor, abductor laryngeal dystonia, any type of vocal fold lesion, or vocal fold paralysis
• known swallowing disorder (oropharyngeal or esophageal), with the exception of transient post-botulinum toxin injection-induced dysphagia
• pregnant
• prisoners
• allergy to topical anesthetic
• cannot fast for 6 hours (4 hour fast prior to study, up to 2 hours to complete the study)
• recent facial trauma
• recent nasal, pharyngeal, laryngeal, or esophageal surgery or obstruction
Ear, Nose & Throat
Clinics and Surgery Center (CSC)
I'm interested
Share via email

Quality of life in patients who have undergone different treatments for upper airway stenosis

The objective of the study is to define quality of life in patients with upper airway stenosis after bypassing the stenosis with either tracheotomy or t-tube stenting. Participants complete surveys over 2 years to collect quality of life information.

Raluca Gray
18 years and over
This study is NOT accepting healthy volunteers
STUDY00015986
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• diagnosis of upper airway stenosis treated with tracheotomy or t-tube.
• seen at the Lions Voice Clinic
• at least 18 years old
• able to complete questionnaires in English without help
Exclusion Criteria:

• require mechanical ventilation
• neurological conditions such as stroke, cerebral palsy, neurodegenerative disease.
• new diagnosis (less than 1 year) of head and neck cancer as the indication for tracheotomy
Breathing, Lung & Sleep Health, Ear, Nose & Throat
Montgomery t-tube, airway stenosis, stenosis, t-tube, trach, tracheotomy, Clinics and Surgery Center (CSC)
I'm interested
Share via email

Vibrotactile stimulation of the larynx to treat unexplained chronic cough

This is a study of adults with unexplained chronic cough between 18-80 years old. This study is trying to determine whether a noninvasive vibrotactile stimulation device can help reduce cough symptoms.

Stephanie Misono
18 years and over
This study is NOT accepting healthy volunteers
STUDY00012174
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:

• adults aged 18-80
• more than 8 weeks of non-productive cough
• chest x-ray or chest CT negative (collected as part of routine clinical care); no time limit on imaging (if available)
• clinical impression that untreated or inadequately treated gastroesophageal, pulmonary, and/or sinus or nasal issue is not the reason for the cough
• able to read and speak English
Exclusion Criteria:

• current smoker or quit less than 3 months ago
• infectious cause for cough (e.g., TB, pertussis, COVID)
• history of known or suspected aspiration pneumonia
• recent intubation/neck surgery (within 8 weeks)
• neuromuscular impairment that may affect cough/laryngeal sensation and/or function (e.g., multiple system atrophy, Parkinson, CVA)
• untreated carotid artery disease
• electronic implants (e.g., pacemaker)
• specific medications (study staff will discuss)
• anticipate use of new medications to treat the cough during the period of the study
• currently having speech therapy for cough
• BMI > 40 (for transmission of VTS through soft tissue)
• allergy to adhesives
• drug/alcohol dependency or abuse
• pregnant
• without regular access to wifi and internet
Breathing, Lung & Sleep Health, Ear, Nose & Throat
chronic cough, cough, larynx, vibrotactile stimulation, Clinics and Surgery Center (CSC)
I'm interested
Share via email
See this study on ClinicalTrials.gov