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Search Results Within Category "Dentistry"

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4 Study Matches

Development and Validation of an MRI-Compatible Jaw Metabolic Stressor Task_Study1

The goal of this study is to develop and test a new way of measuring how much effort and strain the jaw muscles can handle before a person begins to feel specific levels of pain or fatigue. This involves a controlled jaw exercise task designed to better understand the relationship between jaw muscle effort, physical stress in the muscles, and how each person experiences discomfort. It is hoped that the information learned in this study will help researchers refine this new jaw testing method and confirm whether it accurately measures jaw muscle effort and discomfort. This may support future research that improves how jaw pain conditions are understood and eventually lead to better, more individualized treatments for people with jaw muscle and jaw joint disorders.

Principal Investigator: Estephan Moana-Filho
Age Group: 18 years and over
This study is also accepting healthy volunteers
IRB Number: STUDY00026440
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Sex: Male or Female
Age Group: 18 years and over
This study is also accepting healthy volunteers
Inclusion Criteria:

• Had a dental exam in the last year
• No significant body or mouth pain
Exclusion Criteria:

• Certain medical conditions (examples: autism, trigeminal neuralgia, pain conditions)
• Facial hair or significant skin darkening on the cheeks
Conditions: Dentistry
Keywords: Jaw function, JMS
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Neural Correlates of Pain and Alcohol Consumption in Chronic Temporomandibular Disorder (TMD)

The purpose of this research is to better understand how alcohol impacts pain processing in people with Temporomandibular Disorder (TMD) using MRI technology.

Principal Investigator: Jeff Boissoneault
Age Group: 18 years and over
IRB Number: STUDY00022066
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Age Group: 18 years and over
Inclusion Criteria:

• 21 years of age or older
• report regular drinking
• have a diagnosis of a Temporomandibular Disorders
Exclusion Criteria:

• diagnosis of Alcohol Use Disorder
Conditions: Brain & Nervous System, Dentistry, Mental Health & Addiction
Keywords: Alcohol, MRI, Orofacial Pain, Temporomandibular Disorders (TMD)
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Pilot study_Jaw Muscle Metabolic and Brain-Derived Phenotypes of Chronic TMD Pain

The goal of this study is to learn more about a new way of gathering information about a person’s jaw muscle pain – taking scans of the jaw muscles while a person bites down on a special device. It is hoped that the information learned in this study will help the study team to design a bigger study on this new way of learning about jaw muscle pain, which may lead to better, more individualized treatments for jaw muscle pain for future patients.

Principal Investigator: Estephan Moana-Filho
Age Group: 18 years and over
This study is NOT accepting healthy volunteers
IRB Number: STUDY00020619
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Sex: Male or Female
Age Group: 18 years and over
This study is NOT accepting healthy volunteers
Inclusion Criteria:

• age between 18-74 years
• pain-free participants OR chronic jaw pain ( > 3 months),
• have a minimum set of teeth present
Exclusion Criteria:

• certain medical conditions (examples: heart disease, diabetes, autism, trigeminal neuralgia)
• any MRI contraindications (examples: metal implants, claustrophobia)
• left-handed only
Conditions: Dentistry
Keywords: Chronic Jaw Pain, Functional Brain Imaging, Temporomandibular Disorders, TMJ
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Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders

We are studying brain mechanisms related to chronic temporomandibular disorder (TMD) pain. We are looking at brain structural and functional characteristics that can potentially explain why some people experience persistent pain in their jaws for months or years. We will compare this to information we get from people who do not experience TMD pain. We expect that this new knowledge will improve our understanding of this chronic pain condition and help us develop better treatments.

Principal Investigator: Estephan Moana-Filho
Age Group: 18 years and over
This study is also accepting healthy volunteers
IRB Number: STUDY00013924
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Sex: Female
Age Group: 18 years and over
This study is also accepting healthy volunteers
Inclusion Criteria:

• Female participants only (biological sex)
• Age between 18-65 years
• Pain-free participants OR
• Chronic jaw pain ( > 3 months)
Exclusion Criteria:

• Certain medical conditions (examples: heart disease, diabetes, autism, trigeminal neuralgia)
• Any MRI contraindications (examples: metal implants, claustrophobia)
• Being left-handed only
Conditions: Bone, Joint & Muscle, Brain & Nervous System, Dentistry
Keywords: Functional Brain Imaging, Sensory Testing, Temporomandibular Disorders, Jaw Pain, TMJ
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See this study on ClinicalTrials.gov