StudyFinder

A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults with Cutaneous or Oral Lichen Planus or Lichen Planopilaris

Status: Recruiting

The purpose of this study is to learn more about the use of an investigational medicine, called brepocitinib, for the treatment of lichen planopilaris (LPP). Brepocitinib (the “study drug”) is designed to decrease inflammation. The study will look at how safe and effective brepocitinib is and will monitor long-term safety when it is taken for up to 52 weeks. The study drug will be compared to a placebo which is a tablet that looks exactly like the study drug but does not contain any active ingredient.

I'm interested

Sex: Male or Female
Age Group: 18 years and over
This study is NOT accepting healthy volunteers
Inclusion Criteria:

• diagnosed with lichen planopilaris (LPP)
Exclusion Criteria:

• have a history of certain blood or lymphatic system cancers, currently have cancer, or have been treated for most cancers within the past 5 years
• have a high risk of blood clots, heart disease, stroke, or shingles
Interventions:

Drug: Oral Brepocitinib, Drug: Placebo

Conditions:

Dermatology (Skin, Hair & Nails)

Keywords:

Clinics and Surgery Center (CSC), lichen planopilaris, LPP

Study Contact: Jaime Nugent - speck007@umn.edu
Principal Investigator: Maria Hordinsky
Phase: PHASE2
IRB Number: STUDY00027335
See this study on ClinicalTrials.gov

Back