StudyFinder
A randomised, double-blind, placebo-controlled trial with an open-label extension to assess the pharmacokinetics, safety, and efficacy of empagliflozin tablets in paediatric patients with chronic kidney disease (EMPA-KIDNEY® Kids)
Status: Recruiting
This study is for children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a study drug called empagliflozin helps children and adolescents with CKD. Other goals of the study are to find out how empagliflozin is tolerated and handled by the body in children and adolescents with CKD.
Sex: Male or Female
Age Group: Up to 18 years old
Inclusion Criteria:
• 2 to 17 years old
• Chronic kidney disease (CKD) of any type
• on a stable dose of maximally tolerated standard therapy for at least 30 days
• see link to clinicaltrials.gov for complete Inclusion criteria
Exclusion Criteria:
• Type 1 or Type 2 diabetes mellitus
• chronic dialysis or functioning kidney transplant or scheduled for transplantation
• Body mass index (BMI) ≤10th percentile for children ≥4 years of age and ≤25th percentile for children <4 years of age
• gastrointestinal disorders that might interfere withdrug absorption
• see link to clinicaltrials.gov for complete Exclusion criteria
Conditions:
Kidney, Prostate & Urinary
Keywords:
Chronic kidney disease, CKD
Study Contact: Bridget Polfliet - mcken269@umn.edu
Principal Investigator: Michelle Rheault
Phase: PHASE3
IRB Number: STUDY00027290
See this study on ClinicalTrials.gov