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Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

Status: Recruiting

This study is being done to better understand how the brain and impulsive decision-making are connected to depression and suicidal behaviors in people ages 13-21. Participants will complete clinical assessments, behavioral measures, undergo an MRI scan and complete transcranial magnetic stimulation with electroencephalography (TMS-EEG). There will be follow-ups at 6 and 12 months.

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Sex: Male or Female
Age Group: Not specified
This study is NOT accepting healthy volunteers
Inclusion Criteria:

• 13-21 years of age
• current unipolar depressive episode
• lifetime history of suicidal ideation OR suicidal behavior
Exclusion Criteria:

• lifetime history of psychosis, hypomania, mania
• historical diagnosis of autism spectrum disorder or intellectual disability
• pregnancy
• neurological disorders
• MRI contraindications (metal implants, fragments or devices)
Conditions:

Brain & Nervous System, Children's Health, Mental Health & Addiction

Keywords:

adolescents, Depression, mental health, suicide, teens

Study Contact: Ab Flab Study - abflab@umn.edu
Principal Investigator: Kathryn Cullen
Phase: NA
IRB Number: STUDY00020551
See this study on ClinicalTrials.gov

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