StudyFinder
Evaluation of Microbiota Transplant Therapy in Patients with Alopecia Areata
Status: Recruiting
The purpose of this study is to determine if microbiota transplant therapy (MTT) is an effective treatment for patients with alopecia areata, alopecia totalis, and alopecia universalis. We will be testing two different ways of doing the Microbiota transplant therapy (MTT): half the people who choose to be part of this study will take antibiotics before the transplant and half will take placebo antibiotics. We will collect 5 types of samples (2 or more times during the study): blood samples, skin samples, skin swabs, hair, and fecal samples.
Sex: Male or Female
Age Group: 18 years and over
Inclusion Criteria:
• 18 to 75 years of age
• moderate to severe alopecia areata with at least 30% scalp hair loss
• hair loss lasting for at least 3 months
• must be willing to stop using other types of medications to treat Alopecia Areata throughout the study
• evidence of active, ongoing regrowth of hair
• see link to clinicaltrials.gov for complete Inclusion criteria
Exclusion Criteria:
• active medical conditions or cancer
• current gastrointestinal infection or use of antibiotics
• current treatment for gastrointestinal diagnosis or previous GI surgery (past 3 months)
• women who are pregnant or breastfeeding
• see link to clinicaltrials.gov for complete Exclusion criteria
Conditions:
Dermatology (Skin, Hair & Nails)
Keywords:
alopecia, Hair loss
Study Contact: John Meisenheimer - jmeisenh@umn.edu
Principal Investigator: Maria Hordinsky
Phase: PHASE2
IRB Number: STUDY00023721
See this study on ClinicalTrials.gov