
StudyFinder
Senolytics To slOw Progression of Sepsis

Status: Recruiting
Researchers hope that using Fisetin, an antioxidant, will reduce inflammation in the body caused by sepsis, which could help your body and organs have more time to recover. Placebo in this study will be something that looks similar to the study treatment, but does not contain any active drug. Everyone will receive 4 pills, but your group will determine how many of the pills are Fisetin. Researchers will look at the potential effects Fisetin or placebo has on inflammation in the body and how sick participants are at 7 days and 28 days.
Sex: Male or Female
Age Group: 18 years and over
Inclusion Criteria:
• Age 65 or older
• Primary diagnosis of acute infection
• Expected length of hospital stay at least 48 hours
Exclusion Criteria:
• No acute infection
• Known hypersensitivity or allergy to Fisetin
• Not admitted to hospital
• Enrolled in another Sepsis clinical trial
Conditions:
Infectious Diseases
Keywords:
Fisetin, Sepsis
Study Contact: Rojin Ahmadi - rahmadi@umn.edu
Principal Investigator: Michael Puskarich
IRB Number: SITE00001869