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Dissecting the role of acetaldehyde in oral carcinogenesis

Recruiting

The goal of this study is to better understand how drinking alcohol may lead to oral cancers. Acetaldehyde, a chemical formed when the body breaks down alcohol, is believed to play an important role. This study will measure acetaldehyde and DNA damage levels in the mouth of participants after a low dose of alcohol. The levels will be compared between three groups, all having different degrees of risk for developing oral cancer, in order to identify DNA damage that might be crucial to cancer formation.

I'm interested

Male or Female
18 years and over
This study is NOT accepting healthy volunteers
Inclusion Criteria:

• 21 to 45 years of age: alcohol drinker who experiences flushing (reddening or warming of face) when you drink
• 21 to 45 years of age: alcohol drinker who have Fanconi Anemia
• 18 to 45 years of age: non-drinkers
Exclusion Criteria:

• Tobacco or nicotine users

Drug: Alcohol, Procedure: Biospecimen Collection, Procedure: Breath Test

Prevention & Wellness

Alcohol, Fanconi Anemia, drinking

Alcohol Study - alcohol-study@umn.edu
Silvia Balbo
STUDY00012972
See this study on ClinicalTrials.gov

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